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10 Best acetaminophens of 2025

Save up to 24% off
  • Best Choice

    1

    Amazon Basic Care Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, Pain Reliever/Fever Reducer, 500 Count (Packaging may vary)
    Amazon Basic Care

    Amazon Basic Care Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, Pain Reliever/Fever Reducer, 500 Count (Packaging may vary)

    9.7
    Exceptional
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  • Value for Money

    2

    TIME-CAP LABS, INC. Timely Acetaminophen 650 MG - 400 Caplets - Extended Release - Joint Pain Relief, Pain Reliever & Arthritis Pain Relief
    TIME-CAP LABS, INC.

    TIME-CAP LABS, INC. Timely Acetaminophen 650 MG - 400 Caplets - Extended Release - Joint Pain Relief, Pain Reliever & Arthritis Pain Relief

    9.6
    Exceptional
    Our Rating

  • 3

    GoodSense Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, 500 Count
    GoodSense

    GoodSense Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, 500 Count

    9.5
    Excellent
    Our Rating

  • 4

    Amazon Basic Care Acetaminophen Extended-Release Tablets, 650 mg, Arthritis Pain, 400 Count
    Amazon Basic Care

    Amazon Basic Care Acetaminophen Extended-Release Tablets, 650 mg, Arthritis Pain, 400 Count

    9.3
    Excellent
    Our Rating

  • 5

    Amazon Basic Care Rapid Release Acetaminophen Caplets 500 mg, Extra Strength Pain Reliever and Fever Reducer, 400 Count
    Amazon Basic Care

    Amazon Basic Care Rapid Release Acetaminophen Caplets 500 mg, Extra Strength Pain Reliever and Fever Reducer, 400 Count

    9.1
    Excellent
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  • 6

    Amazon Basic Care Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, Pain Reliever/Fever Reducer, 100 Count (Packaging may vary)
    Amazon Basic Care

    Amazon Basic Care Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, Pain Reliever/Fever Reducer, 100 Count (Packaging may vary)

    8.9
    Very Good

  • 7

    Tylenol Extra Strength Acetaminophen Rapid Release Gels, Extra Strength Pain Reliever & Fever Reducer, Gelcaps with Laser-Drilled Holes, 500 mg Acetaminophen, 100 ct
    Tylenol

    Tylenol Extra Strength Acetaminophen Rapid Release Gels, Extra Strength Pain Reliever & Fever Reducer, Gelcaps with Laser-Drilled Holes, 500 mg Acetaminophen, 100 ct

    24% Off
    8.8
    Very Good
    Our Rating

  • 8

    Tylenol Regular Strength Tablets with 325 mg of Acetaminophen, Fever Reducer & Pain Reliever for Headache, Backache, Muscle Aches, Joint Pain & Menstrual Cramps, 100 ct
    Tylenol

    Tylenol Regular Strength Tablets with 325 mg of Acetaminophen, Fever Reducer & Pain Reliever for Headache, Backache, Muscle Aches, Joint Pain & Menstrual Cramps, 100 ct

    8.6
    Very Good

  • 9

    GeriCare Extra Strength Acetaminophen Pain Relief Fever Reducer Tablets, Strength 500mg Tablet | Joint, Muscle, Arthritis, Back Pain Relief 100 Count (Pack of 1)
    GeriCare

    GeriCare Extra Strength Acetaminophen Pain Relief Fever Reducer Tablets, Strength 500mg Tablet | Joint, Muscle, Arthritis, Back Pain Relief 100 Count (Pack of 1)

    8.4
    Good

  • 10

    HealthA2Z® Extra Strength Pain Relief | Acetaminophen 500mg | Contains No Aspirin | Fever Reducer | Pain Reliever (500 Count (Pack of 1))
    HealthA2Z

    HealthA2Z® Extra Strength Pain Relief | Acetaminophen 500mg | Contains No Aspirin | Fever Reducer | Pain Reliever (500 Count (Pack of 1))

    8.3
    Good